First reason is that you will get to wipe all the infected and wasted items from your Mac computer that may slow down the system. Removing junk from Mac is beneficial and crucial for various reasons.
So, it's highly recommend to remove all junk files on your Mac regularly.
It's useless to keep these junk files live on your system, they not only will slow down your Mac performance, but also they may cause some unknown errors and glitches. We know that junks file can be easily and continually generated without any permission, it will take up lot of space on your RAM or hard drive.